MOLECULAR CHARACTERIZATION OF THE XENOPUS-LAEVIS CHAPERONIN GENE CCTG

Authors
WALKLEY NA PAGE RA MALIK AN
Citation
Na. Walkley et al., MOLECULAR CHARACTERIZATION OF THE XENOPUS-LAEVIS CHAPERONIN GENE CCTG, Biochimica et biophysica acta, N. Gene structure and expression, 1309(1-2), 1996, pp. 25-30
Citations number
17
Categorie Soggetti
Biology,Biophysics,"Biothechnology & Applied Migrobiology
Journal title
Biochimica et biophysica acta, N. Gene structure and expression → ACNP
ISSN journal
01674781
Volume
1309
Issue
1-2
Year of publication
1996
Pages
25 - 30
Database
ISI
SICI code
0167-4781(1996)1309:1-2<25:MCOTXC>2.0.ZU;2-W
Abstract
By library screening and PCR we have obtained cDNA clones which encode the gamma subunit of the CCT chaperonin complex from Xenopus laevis. The gene (XlCctg), which encodes the CCT gamma subunit contains an ope n reading frame which codes for 547 amino acid residues (60 kDa) and t he predicted amino acid sequence shares a high degree of sequence iden tity with other CCT gamma homologues. The XlCctg mRNA measures 2.1 kb and is expressed ubiquitously in all of the X. laevis tissues examined . The mRNA levels of XlCctg are significantly higher in the ovary comp ared with other tissues.