MONOBALLISM REVEALING MULTIPLE-SCLEROSIS - NEURORADIOLOGICAL ASPECTS

A 38-year-old woman suddenly showed signs of monoballism in the right upper limb. Examination of CSF show ed 13 monocytes per mm(3) and 28.7 % of IgG in oligoclonal bands. MRI examination showed several high sig nal lesions in T-2-weighted images. One of these lesions was located i n the left subthalamic region. Visual evoked potentials showed increas ed latencies for the P100 wave on the left eye. Two years later she ex perienced vertigo, diplopia, gait unsteadiness and left facial dysesth esia This clinical syndrome almost completely regressed after 10 days of ACTH therapy (Synacthene). Diagnosis of multiple sclerosis was supp orted by radiological and neurophysiological investigations.