We explicitly extract the structure of higher-derivative curvature-squ
ared terms at genus 0 and 1 in the d=4 heterotic string effective acti
on compactified on symmetric orbifolds by computing on-shell S-matrix
superstring amplitudes. In particular, this is done within the context
of calculating the graviton 4-point amplitude. We also discuss the mo
duli-dependent gravitational threshold corrections to the coupling ass
ociated with the CP even quadratic curvature terms.