MEASUREMENT OF METHEMOGLOBIN AFTER EMLA(R) ANALGESIA FOR NEWBORN CIRCUMCISION

Authors
LAW RMT HALPERN S MARTINS RF REICH H INNANEN V OHLSSON A
Citation
Rmt. Law et al., MEASUREMENT OF METHEMOGLOBIN AFTER EMLA(R) ANALGESIA FOR NEWBORN CIRCUMCISION, Biology of the neonate, 70(4), 1996, pp. 213-217
Citations number
12
Categorie Soggetti
Pediatrics
Journal title
Biology of the neonate → ACNP
ISSN journal
00063126
Volume
70
Issue
4
Year of publication
1996
Pages
213 - 217
Database
ISI
SICI code
0006-3126(1996)70:4<213:MOMAEA>2.0.ZU;2-6
Abstract
A statistically significant (p = 0.049) increase in methemoglobin (Met Hb), which did not exceed normal values, was noted 8 h after applicati on of 1 g of EMLA(R) (Eutectic Mixture of Local Anesthetics) to the fo reskin of 10 normal newborns to reduce pain associated with circumcisi on. The highest MetHb concentration observed was 3 g/l (toxic > 50 g/l ). No infant showed clinical signs of methemoglobinemia. We conclude t hat EMLA(R) is safe to use as a local anesthetic in term neonates.