ASYMPTOMATIC ELEVATION OF ALKALINE-PHOSPH ATASES SECONDARY TO BENIGN FAMILIAL HYPERPHOSPHATASEMIA - REPORT OF ONE CASE

We report a 33 years old man consulting for abdominal pain. Initial di agnostic work up showed high levels of alkaline phosphatases, that wer e confirmed in a new blood sample. Using electrophoresis, total alkali ne phosphatases were 198 U/l (normal values= 30-117) and the bone frac tion was 101 U/l (normal values= 0-35). Bone scintiscan and endocrinol ogical assessment were normal. One year later, the same values persist ed. Studying the family, three of four brothers had the same alteratio ns in alkaline phosphatases. It was concluded that these subjects had the rare condition known as benign familial hyperphosphatasemia.