SYNTHESIS AND STUDY OF IMMOBILIZED INSULIN

Authors
VALUEV IL VALUEV LI SYTOV GA PLATE NA
Citation
Il. Valuev et al., SYNTHESIS AND STUDY OF IMMOBILIZED INSULIN, Biochemistry, 61(9), 1996, pp. 1121-1124
Citations number
20
Categorie Soggetti
Biology
Journal title
Biochemistry → ACNP
ISSN journal
00062979
Volume
61
Issue
9
Year of publication
1996
Pages
1121 - 1124
Database
ISI
SICI code
0006-2979(1996)61:9<1121:SASOII>2.0.ZU;2-5
Abstract
Conjugates of insulin with duck egg-white ovomucoid and soybean trypsi n inhibitor were synthesized. The conjugates were highly stable to alp ha-chymotrypsin treatment. Peroral administration of the insulin-ovomu coid conjugate to rabbits, in contrast to the insulin-soybean trypsin inhibitor conjugate, statistically significantly lowered blood glucose level.