ADDITIONAL ANTIBACTERIAL DITERPENES FROM THE BARK OF JUNIPERUS-PROCERA

Citation
I. Muhammad et al., ADDITIONAL ANTIBACTERIAL DITERPENES FROM THE BARK OF JUNIPERUS-PROCERA, PTR. Phytotherapy research, 10(7), 1996, pp. 604-607
Citations number
18
Categorie Soggetti
Chemistry Medicinal","Pharmacology & Pharmacy
Journal title
ISSN journal
0951418X
Volume
10
Issue
7
Year of publication
1996
Pages
604 - 607
Database
ISI
SICI code
0951-418X(1996)10:7<604:AADFTB>2.0.ZU;2-L
Abstract
The bark of Juniperus procera a yielded the diterpene 7 beta-hydroxyab ieta-8,13-dien-11,12-dione (1) with strong activity against Mycobacter ium species, and the hitherto unreported bisnorlabdane derivative 14,1 5-bisnor-13-oxolabd-8(17),11(E)-dien-19-oic acid (4), In addition, the bark yielded the known compounds crypotrienolic acid, isocupressic ac id and sugiol. Structural assignments were largely based on the spectr al data, including those derived from 2D NR IR COSY and HETCOR experim ents.