R. Rastogi et al., EFFECT OF PICROLIV ON RIFAMPICIN-INDUCED BIOCHEMICAL-CHANGES IN THE RAT-LIVER AND SERUM, PTR. Phytotherapy research, 10(7), 1996, pp. 610-612
Rifampicin was administered to rats (50 mg/kg, i.p. daily) for 2, 6, 1
2 or 24 days and selected biochemical parameters in liver and serum we
re measured 24h after the last injection, Concomitant administration o
f picroliv (12 mg/kg) showed maximum hepatoprotective activity in the
6 dag schedule, Administration of picroliv during the recovery phase I
n 12 and 24 day schedule expedited recovery of most parameters.