Using the heterotic-type II duality of N = 2 string vacua in four spac
e-time dimensions we study non-perturbative couplings of toroidally co
mpactified six-dimensional heterotic vacua, In particular, the heterot
ic-heterotic S-duality and the Coulomb branch of tensor multiplets obs
erved in six dimensions are studied from a four-dimensional point of v
iew. We explicitly compute the couplings of the vector multiplets of s
everal type II vacua and investigate the implications for their hetero
tic duals.