EFFECT OF IN-VITRO INFECTION OF HUMAN MONOCYTES WITH LOW NUMBERS OF MYCOBACTERIUM-TUBERCULOSIS BACTERIA ON MONOCYTE APOPTOSIS

Authors
DURRBAUMLANDMANN I GERCKEN J FLAD HD ERNST M
Citation
I. Durrbaumlandmann et al., EFFECT OF IN-VITRO INFECTION OF HUMAN MONOCYTES WITH LOW NUMBERS OF MYCOBACTERIUM-TUBERCULOSIS BACTERIA ON MONOCYTE APOPTOSIS, Infection and immunity, 64(12), 1996, pp. 5384-5389
Citations number
23
Categorie Soggetti
Immunology,"Infectious Diseases
Journal title
Infection and immunity → ACNP
ISSN journal
00199567
Volume
64
Issue
12
Year of publication
1996
Pages
5384 - 5389
Database
ISI
SICI code
0019-9567(1996)64:12<5384:EOIIOH>2.0.ZU;2-M
Abstract
The effect of Mycobacterium tiberculosis H37Rv on spontaneous apoptosi s of human monocytes from healthy donors in vitro was investigated. In fection with low numbers of viable M. tuberculosis bacteria prevented spontaneously occurring apoptosis in monocytes. Our data suggest that apoptosis of monocytes appears to be negatively associated with the pr esence of tumor necrosis factor alpha.