Introduction: Transcranial Doppler ultrasonography (TCD) and magnetic
resonance angiography (MRA) are well-established techniques for ascert
aining intracranial obstructive artery disease. The short examination
time required for additional helical CT angiography (CTA) allows quick
management of emergency patients already undergoing native CT. Howeve
r, today the ability of CTA to detect stenoses of the middle cerebral
artery (MCA) has not been proven. To analyse the value of CTA in the c
lassification of atherosclerotic disease 23 MCA stenoses confirmed by
TCD and MRA were investigated. Methods: CTA was performed on a Hispeed
advantage scanner (GE) using a bolus injection of 70 ml KM and 40 mi
NaCl with a Row rate of 2.5 ml/s, a thickness of 1 mm, a pitch of 1.5
and a 1 mm increment. CTA was presented as maximum intensity projectio
n (MIP) and as multi-projection volume reconstruction (MPVR). A three-
step classification of stenosis was compared with the results of TCD a
nd MRA. Results: Good opacification of the MCA was achieved in MI and
M2 segments in all patients. Classification of stenosis by CTA agreed
with MRA and TCD in 14 cases: 7 stenoses were assigned to a lower clas
sification by CTA. Two low-grade stenoses could not be proven by CTA,
Although MIP and MPVR yield the same result in stenosis classification
MPVR showed a sharper image quality. In contrast to MRA, veins were h
ighly opacified in CTA, Artery and vein were sometimes superimposed, w
hich had to be avoided by changing the projection angle. Conclusion: M
edium- and high-grade MCA stenoses can be demonstrated by CTA quickly
and reliably. Compared to MRA and TCD, CTA provides lower grading of s
tenosis.