S. Laalami et al., MESSENGER-RNA TRANSLATION IN PROKARYOTES - GTPASE CENTERS ASSOCIATED WITH TRANSLATIONAL FACTORS, Biochimie, 78(7), 1996, pp. 577-589
During the decoding of messenger RNA, each step of the translational c
ycle requires the intervention of protein factors and the hydrolysis o
f one or more GTP molecule(s). Of the prokaryotic translational factor
s, IF2, EF-Tu, SELB, EF-G and RF3 are GTP-binding proteins. In this re
view we summarize the latest findings on the structures and the roles
of these GTPases in the translational process.