PAX GENES AND THEIR ROLES IN CELL-DIFFERENTIATION AND DEVELOPMENT

Authors
MANSOURI A HALLONET M GRUSS P
Citation
A. Mansouri et al., PAX GENES AND THEIR ROLES IN CELL-DIFFERENTIATION AND DEVELOPMENT, Current opinion in cell biology, 8(6), 1996, pp. 851-857
Citations number
78
Categorie Soggetti
Cell Biology
Journal title
Current opinion in cell biology → ACNP
ISSN journal
09550674
Volume
8
Issue
6
Year of publication
1996
Pages
851 - 857
Database
ISI
SICI code
0955-0674(1996)8:6<851:PGATRI>2.0.ZU;2-0
Abstract
Members of the Pax gene family are expressed in various tissues during ontogenesis. Evidence for their crucial role in morphogenesis, organo genesis, cell differentiation and oncogenesis is provided by rodent mu tants and human diseases. Additionally, recent experimental in vivo an d in vitro approaches have led to the identification of molecules that interact with Pax proteins.