ZEBRAFISH - TOOLS FOR INVESTIGATING CELLULAR-DIFFERENTIATION

Authors
STEMPLE DL DRIEVER W
Citation
Dl. Stemple et W. Driever, ZEBRAFISH - TOOLS FOR INVESTIGATING CELLULAR-DIFFERENTIATION, Current opinion in cell biology, 8(6), 1996, pp. 858-864
Citations number
70
Categorie Soggetti
Cell Biology
Journal title
Current opinion in cell biology → ACNP
ISSN journal
09550674
Volume
8
Issue
6
Year of publication
1996
Pages
858 - 864
Database
ISI
SICI code
0955-0674(1996)8:6<858:Z-TFIC>2.0.ZU;2-A
Abstract
Two recent large-scale genetic screens in zebrafish have identified ma ny mutations that affect differentiation in a variety oi organ systems , particularly the notochord, the neural crest and the blood. The comb ination of these newly identified mutations and well established embry ological methods makes zebrafish uniquely suited among vertebrate expe rimental systems to simultaneously address the roles of specific genes and specific cell-cell interactions during differentiation.