RECEIVED PHYSICOCHEMICAL FEATURES OF L-3, 4-DIHYDROXYPHENYLALANINE (DOPA) AND DOPAMINE ENCAPSULATED IN LIPOSOMES

Authors
BORISOVA NV KAPLUN AP BOGOMOLOV OV GRIGOREV VB YURASOV VV NIKUSHKIN EV KRYZHANOVSKII GN SHVETS VI
Citation
Nv. Borisova et al., RECEIVED PHYSICOCHEMICAL FEATURES OF L-3, 4-DIHYDROXYPHENYLALANINE (DOPA) AND DOPAMINE ENCAPSULATED IN LIPOSOMES, Bioorganiceskaa himia, 22(10-11), 1996, pp. 846-851
Citations number
26
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Bioorganiceskaa himia → ACNP
ISSN journal
01323423
Volume
22
Issue
10-11
Year of publication
1996
Pages
846 - 851
Database
ISI
SICI code
0132-3423(1996)22:10-11<846:RPFOL4>2.0.ZU;2-C
Abstract
L-3,4-Dihydroxyphenylalanime (DOPA) and dopamine encapsulated in lipos omes have been obtained. These preparations can be used as drugs for P arkinson's disease. The level of encapsulation of the compounds under study in liposomes and their partition coefficients have been determin ed. The kinetics of DOPA (or dopamine) exit from the liposomes have be en studied.