MODIFIED TRIPHOSPHATES OF CARBOCYCLIC NUCLEOSIDE ANALOGS - SYNTHESIS,STABILITY TOWARDS ALKALINE-PHOSPHATASE AND SUBSTRATE PROPERTIES FOR SOME DNA-POLYMERASES
N. Dyatkina et al., MODIFIED TRIPHOSPHATES OF CARBOCYCLIC NUCLEOSIDE ANALOGS - SYNTHESIS,STABILITY TOWARDS ALKALINE-PHOSPHATASE AND SUBSTRATE PROPERTIES FOR SOME DNA-POLYMERASES, Bioorganic & medicinal chemistry letters, 6(22), 1996, pp. 2639-2642
New triphosphate derivatives of carbocyclic nucleoside analogues have
been synthesized and shown to be potent substrates for terminal deoxyn
ucleotidyltransferase and/or HIV reverse transcriptase; the compounds
are stable to dephosphorylation with human placental alkaline phosphat
ase. Copyright (C) 1996 Elsevier Science Ltd