SYNTHESIS OF PHOSPHINIC ACID TRANSITION-STATE ANALOGS FOR THE REACTION CATALYZED BY KYNURENINASE

Authors
ROSS FC BOTTING NP LEESON PD
Citation
Fc. Ross et al., SYNTHESIS OF PHOSPHINIC ACID TRANSITION-STATE ANALOGS FOR THE REACTION CATALYZED BY KYNURENINASE, Bioorganic & medicinal chemistry letters, 6(22), 1996, pp. 2643-2646
Citations number
10
Categorie Soggetti
Chemistry Inorganic & Nuclear","Chemistry Medicinal
Journal title
Bioorganic & medicinal chemistry letters → ACNP
ISSN journal
0960894X
Volume
6
Issue
22
Year of publication
1996
Pages
2643 - 2646
Database
ISI
SICI code
0960-894X(1996)6:22<2643:SOPATA>2.0.ZU;2-7
Abstract
The syntheses of phosphinic acid and methyl phosphinate analogues of k ynurenine, designed as transition state mimics for the enzyme kynureni nase ate described, along with their inhibitory properties. Copyright (C) 1996 Elsevier Science Ltd