Z1046, A NOVEL PERIPHERAL DOPAMINERGIC AGENT

Authors
MONTANARI S BERTOLINI G CASAGRANDE C CAVALLERI P FERLENGA P MARCHINI F PRADELLA L POCCHIARI F SANTANGELO F SEMERARO C
Citation
S. Montanari et al., Z1046, A NOVEL PERIPHERAL DOPAMINERGIC AGENT, Bioorganic & medicinal chemistry letters, 6(22), 1996, pp. 2795-2800
Citations number
13
Categorie Soggetti
Chemistry Inorganic & Nuclear","Chemistry Medicinal
Journal title
Bioorganic & medicinal chemistry letters → ACNP
ISSN journal
0960894X
Volume
6
Issue
22
Year of publication
1996
Pages
2795 - 2800
Database
ISI
SICI code
0960-894X(1996)6:22<2795:ZANPDA>2.0.ZU;2-Y
Abstract
The D-1-like, D-2-like, alpha(1) and alpha(2) in vitro activities of 2 -aminotetraline congeners are reported. Z1046 was selected and the ant ihypertensive activity in rat and dog was evaluated both by intravenou s and oral routes. Copyright (C) 1996 Elsevier Science Ltd