CLINICAL-APPLICATION OF NONSELECTIVE ASSISTED HATCHING OF HUMAN EMBRYOS

Objective: To evaluate the effect of nonselective assisted hatching on pregnancy rate (PR) and to provide an alternative and simplified meth od for clinical application of assisted hatching. Design: Retrospectiv e analysis of clinical data. Setting: Private infertility practice. Pa tient(s): Women from 258 consecutive stimulated IVF cycles. Interventi on(s): Assisted hatching was performed on each transferred embryo rega rdless of patient history, embryo morphology, or other selection crite ria routinely applied to many IVF programs. Main Outcome Measure(s): P regnancy, live birth, and implantation rates. Result(s): Of 258 consec utive patients who had nonselective assisted hatching, 109 (42%) had c linical pregnancies, with 93 (36%) live births and 178 (20%) embryos i mplanted. Conclusion(s): Nonselective assisted hatching resulted in an acceptable PR and provided an alternative and simplified method for c linical application of assisted hatching.