The largest series of normal singleton placental weights was collected
in the Collaborative Perinatal Study between the years 1959 and 1966
but values for normal twin placental weights were not published. In ou
r study we examined 787 singleton and 514 twin normal placentas. Place
ntas with associated conditions known to affect the weights of placent
as were excluded. After establishing the normal values for singleton a
nd twin placental weights, we concluded that weight gain of twin place
ntas appears to accelerate between 24 and 36 weeks but reaches a plate
au after 37 weeks, whereas singleton placentas appear to gain weight m
ore uniformly throughout gestation. The mean values of twin placental
weights for each gestational age are less than double those of singlet
on placental weights for the same duration of gestation. Our singleton
and twin placentas are heavier than those from previously published d
ata and may reflect a generational or nutritional change over the 30 y
ears since the original numbers were compiled.