TUBULORETICULAR STRUCTURES INDUCED BY ROTAVIRUS INFECTION IN HT-29 CELLS

Authors
TINARI A AMMENDOLIA MG SUPERTI F DONELLI G
Citation
A. Tinari et al., TUBULORETICULAR STRUCTURES INDUCED BY ROTAVIRUS INFECTION IN HT-29 CELLS, Ultrastructural pathology, 20(6), 1996, pp. 571-576
Citations number
24
Categorie Soggetti
Microscopy,Pathology
Journal title
Ultrastructural pathology → ACNP
ISSN journal
01913123
Volume
20
Issue
6
Year of publication
1996
Pages
571 - 576
Database
ISI
SICI code
0191-3123(1996)20:6<571:TSIBRI>2.0.ZU;2-P
Abstract
An electron microscopic study addressed morphological changes induced by rotavirus in the enterocyte-like cell line HT-29. Tubuloreticular s tructures were found in the latest stages of viral infection when cell s, undergoing a cytopathic effect, detached from the substrate. Tubulo reticular structures were localized, together with viral particles, wi thin highly dilated perinuclear cisternae. The results suggest that tu buloreticular structures evolve during interaction of rotavirus with t he rough endoplasmic reticulum membranes.