Jm. Holbert et al., CHANGES IN LUNG-VOLUME AND VOLUME OF EMPHYSEMA AFTER UNILATERAL LUNG REDUCTION SURGERY - ANALYSIS WITH CT LUNG DENSITOMETRY, Radiology, 201(3), 1996, pp. 793-797
PURPOSE: To evaluate changes in volume of the lungs and volume of emph
ysema after unilateral lung reduction surgery (ULRS) by using computed
tomographic (CT) lung densitometry. MATERIALS AND METHODS: Twenty-eig
ht patients underwent CT before and 3 months after ULRS. With use of a
density mask software program and a three-dimensional graphics workst
ation, CT scans were analyzed to define the volume of the lungs and th
e volume of emphysema. Pre- and postoperative mean CT numbers were det
ermined. RESULTS: After ULRS, the surgically reduced lung volume decre
ased 22%, and the intact opposite lung volume increased 4%. Emphysema
in the surgically reduced lung decreased 14% and was unchanged in the
intact opposite lung. Mean CT numbers in the surgically reduced lung i
ncreased 26 HU but were unchanged in the intact opposite lung. CONCLUS
ION: The effects of ULRS on each lung can be evaluated by using CT lun
g densitometry and a three-dimensional graphics workstation. ULRS redu
ces emphysema and lung volume in the surgically reduced lung without s
tatistically significant worsening of contralateral emphysema at 3 mon
ths.