Am. Jeremijenko et al., THE HIGH MORBIDITY ASSOCIATED WITH A MEASLES OUTBREAK IN A WEST AUSTRALIAN TOWN, Journal of paediatrics and child health, 32(5), 1996, pp. 382-385
Objective: To determine the effectiveness of the measles vaccine and t
o record the morbidity during a measles outbreak. Methodology: A retro
spective cohort study was carried out. It was a community-based study
in Bunbury, Western Australia, between February and May 1994, of 53 ca
ses of measles and their household contacts. Results: Of the 53 cases
of measles, 24 were from one high school. Only two cases occurred in t
he high school class that had received the National Health and Medical
Research Council of Australia recommended measles, mumps and rubella
(MMR) booster 12 months earlier. Neither had been vaccinated. Vaccine
effectiveness was 91% (95% confidence interval 67-97%). Ten cases had
complications of measles and a further five were admitted to hospital.
Doctors prescribed antibiotics to 29 cases and metoclopramide to five
cases. One month elapsed between the day the index case became ill an
d the first notification to the community health centre. Conclusions:
The low herd immunity that led to this high school outbreak can be att
ributed to low vaccine coverage. There was a significant morbidity ass
ociated with this outbreak that may have been averted if earlier notif
ication had occurred. The MMR booster dose should be offered to all 10
-16 year olds to prevent high school outbreaks.