ERRORS EVOLUTION AND ANALYSIS IN ANTINEOPLASTIC DRUG PREPARATION DURING ONE-YEAR

We analyzed the errors occurring in the preparation circuit of cytotox ic mixtures of the Centralized Cytotoxic Preparation Unit during one y ear. Analysis of their evolution meant the investigation of twenty par ameters susceptible to error. Each parameter was considered one error opportunity. Error has been defined either by the lack of data or mist ake in the controlled parameter, in 4,734 preparations (94,680 paramet ers) there were 314 errors. The percentage of error per parameter in t he first month of study was 0.74; at sixth was 0.34 and the las month was 0.26. Only in four months the day of maximum number of preparation s coincided with the day of maximum number of errors. We conclude that the percentage of errors in the preparation process is low with a ten dency to decrease and that the number of daily preparations is not the single factor that influences the production of errors.