We examined the prevalence of fatigue and its association with occupat
ional conditions and health-related habits in 3785 industrial employee
s of six industrial sectors to define modifiable factors. The factors
examined included complaints of fatigue during and after work, an ergo
nomic evaluation of employees' workstations, demographic characteristi
cs, and health-related habits, Eighteen percent of the subjects compla
ined of severe fatigue frequently or very frequently. We were able to
identify two major modifiable variables that were independently associ
ated with the presence of fatigue. Logistic regression showed that tho
se workers who did not participate in physical activity at least once
a week had a 1.7-fold increase in prevalence of severe fatigue (95% co
nfidence interval = 1.3 to 2.3, P < 0.001), The other major modifiable
factor was temperature control, with those workers who worked at non-
temperature-controlled workstations having a 50% increase in the preva
lence of fatigue (odds ratio = 1.5, 95% CI = 1.1 to 2.1; P = 0.01). Ac
cidents were significantly more frequent in those workers with fatigue
, Further studies should focus on intervention programs to modify the
factors identified by this study.