F. Maroun et al., HISTORICAL VIGNETTE - CEREBRAL CORTICAL STIMULATION AND SURGERY FOR EPILEPSY, Canadian journal of neurological sciences, 23(4), 1996, pp. 303-307
In 1909, in an isolated community hospital, on the northern tip of the
Province of Newfoundland and Labrador, Canada, Dr, John Mason Little,
Jr, performed electrical stimulation of the cerebral cortex, prior to
cortical excision, as treatment of recurrent cerebral seizures in thr
ee patients, Extracts from Dr, Little's written records of the clinica
l features, the neurosurgical procedures and cerebral cortical stimula
tion are summarised, A brief review of the contemporaneous history of
neurosurgical procedures for epilepsy provides a prospective of Dr, Li
ttle's remarkable surgical virtuosity.