GABAPENTIN

Gabapentin is a novel antiepileptic drug that has recently been introd uced in Canada, Although its mechanism of action remains to be defined gabapentin is effective In a number of seizure models which predict: its efficacy in partial and tonic-clonic seizures, Clinical studies su pport the clinical efficacy of gabapentin as adjunctive therapy in adu lts with epilepsy with partial and secondarily generalized tonic-cloni c seizures. Gabapentin has a favorable pharmacokinetic profile and is generally well tolerated. More clinical data are required on the role of gabapentin in children and additional monotherapy experience is req uired before the role of gabapentin in the overall treatment of epilep sy can be better defined.