Ejaculatory disorders can interfere with the fertility of young adults
who suffer from spinal cord injury, have type I diabetes mellitus or
have undergone retroperitoneal or intrapelvic operations. Following an
overview of causes and treatment of ejaculatory disorders, the data o
f our centre are presented. From a group of 37 patients with genuine l
oss of seminal emission, 15 men and their wives were offered a combine
d treatment of rectal probe electro-ejaculation and artificial reprodu
ctive techniques. No serious complications occurred. During 40 cycles
with intracorporeal insemination and 11 cycles with extracorporeal fer
tilization techniques, seven pregnancies were achieved, representing a
pregnancy rate of 46% per couple and 14% per cycle for all cycles. Fi
ve healthy children were born, all following extracorporeal inseminati
on. The 'take-home baby rate' for this population and for this techniq
ue is 45%. In vitro fertilization (IVF) led to one birth, intracytopla
smic sperm injection (ICSI) achieved four live births out of three pre
gnancies, one being a twin gestation. Since our successes are due to t
he use of extracorporeal insemination techniques, these are now incorp
orated in a new, more rational treatment protocol.