M. Turgut et al., EFFECT OF ND-YAG LASER ON EXPERIMENTAL DISC DEGENERATION .2. HISTOLOGICAL AND MR-IMAGING FINDINGS, Acta neurochirurgica, 138(11), 1996, pp. 1355-1361
The potential advantages of percutaneous procedures over traditional d
iscectomy are multiple, but the use of laser energy to ablate disc tis
sue appears entirely empirical. To date, no experimental study exists
investigating the results of laser on degenerated intervertebral disc.
The present study was therefore undertaken to determine the histologi
cal and radiological changes induced by neodymium-yttrium-aluminum-gar
net (Nd:YAG) laser on such disc tissue. It was shown that the vaporiza
tion of disc tissue was caused by Nd:YAG laser in the early period, bu
t this was gradually replaced by cartilaginous fibrous tissue at 60 da
ys after laser irradiation as a result of the proliferation of cartila
ginous cells and fibrous tissues. Accordingly the magnetic resonance (
MR) imaging index histogram moved to the left in the early period, but
it moved to the right again at 60 days after laser irradiation. In vi
ew of these data, we conclude that the use of laser in degenerated dis
c disease does not represent an effective treatment as an alternative
to conventional surgical methods.