ELIMINATION OF TRANSAMINATION SIDE PRODUCT BY THE USE OF DC(AC) METHYLPHOSPHONAMIDITE IN THE SYNTHESIS OF OLIGONUCLEOSIDE METHYLPHOSPHONATES

Authors
REDDY MP FAROOQUI F HANNA NB
Citation
Mp. Reddy et al., ELIMINATION OF TRANSAMINATION SIDE PRODUCT BY THE USE OF DC(AC) METHYLPHOSPHONAMIDITE IN THE SYNTHESIS OF OLIGONUCLEOSIDE METHYLPHOSPHONATES, Tetrahedron letters, 37(48), 1996, pp. 8691-8694
Citations number
12
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron letters → ACNP
ISSN journal
00404039
Volume
37
Issue
48
Year of publication
1996
Pages
8691 - 8694
Database
ISI
SICI code
0040-4039(1996)37:48<8691:EOTSPB>2.0.ZU;2-M
Abstract
The transamination side product formed by the use of dC(bz) or dC(ibu) methylphosphonamidite upon treatment with ethylenediamine has been el iminated by the use of dC(Ac) methylphosphonamidite. The synthesis and characterization of DMT dC(Ac) methylphosphonamidite is described. Co pyright (C) 1996 Elsevier Science Ltd