REVERSIBLE DEACTIVATION OF CEREBRAL NETWORK COMPONENTS

Citation
Br. Payne et al., REVERSIBLE DEACTIVATION OF CEREBRAL NETWORK COMPONENTS, Trends in neurosciences, 19(12), 1996, pp. 535-542
Citations number
67
Categorie Soggetti
Neurosciences
Journal title
ISSN journal
01662236
Volume
19
Issue
12
Year of publication
1996
Pages
535 - 542
Database
ISI
SICI code
0166-2236(1996)19:12<535:RDOCNC>2.0.ZU;2-P
Abstract
Reversible deactivation techniques have shown that the cerebral networ k: (1) is dynamic, its functions depending on contemporaneous processi ng elsewhere in the network; (2) is composed of single nodes that cont ribute to several behaviors; (3) possesses an inherent plasticity that tends to minimize lesion-induced deficits; and (4) comprises feedforw ard and lateral connections that contribute in different ways to netwo rk operations. The next major advances in understanding network operat ions will probably be made by applying a combination of behavioral, ne uron-recording and deactivation techniques. The greatest near-term gai ns ave likely to be made in understanding the contributions that feedb ack projections make to cerebral network function.