A SHORT ENANTIOSELECTIVE FORMAL SYNTHESIS OF METHYL (S)-(-)-6,8-DIHYDROXYOCTANOATE - A KEY INTERMEDIATE FOR THE SYNTHESIS OF R-(-ALPHA-LIPOIC ACID())

Authors
BEZBARUA MS SAIKIA AK BARUA NC KALITA D GHOSH AC
Citation
Ms. Bezbarua et al., A SHORT ENANTIOSELECTIVE FORMAL SYNTHESIS OF METHYL (S)-(-)-6,8-DIHYDROXYOCTANOATE - A KEY INTERMEDIATE FOR THE SYNTHESIS OF R-(-ALPHA-LIPOIC ACID()), Synthesis, (11), 1996, pp. 1289
Citations number
23
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Synthesis → ACNP
ISSN journal
00397881
Issue
11
Year of publication
1996
Database
ISI
SICI code
0039-7881(1996):11<1289:ASEFSO>2.0.ZU;2-#
Abstract
A short enantioselective formal synthesis of methyl (S)-(-)-6,8-dihydr oxyoctanoate starting from readily available 2-nitrocyclohexanone usin g a novel retro-Henry reaction is described.