We describe a 34-year-old man with acute, nontraumatic inferior branch
oculomotor nerve palsy. Complete ophthalmologic, neurologic, and syst
emic examinations were otherwise normal. The oculomotor nerve palsy re
served, but the patient subsequently developed bilateral upper extremi
ty numbness and painful dysesthesias in the distribution of the median
nerves. These observations suggest that inferior branch oculomotor ne
rve palsy, although uncommon, may occur as part of a more generalized
neurologic disorder, presumed in our patient to be either vasculitic o
r demyelinating in nature.