The first priority when treating infected bone and soft-tissue defects
is the maintenance or reconstruction of vitality, vascularity and sta
bility. This means that when signs of infection are apparent, this is
an immediate indication for operative revision with protective prepara
tions on the tissue and radical debridement. Treatment of the soft-tis
sue damage is carried out with local or microsurgically connected musc
le flaps. As for stability, in early infection the retention of well-b
onded implants is often possible. If not, it is often necessary to cha
nge over to external fixation. Reconstruction of bone damage is carrie
d out after the infection recedes, and complete healing is finally ach
ieved by further treatment changes to conservative means or further st
abilizing treatment.