EXOGENOUS GANGLIOSIDES MODIFY BIOCHEMICAL-CHANGES ASSOCIATED WITH THEDEVELOPMENT OF FETAL CHICKEN NERVOUS-TISSUE IN CULTURE

Authors
MATYUSHICHEV VB SOKOLOV IN NALIVAEVA NN SAFRONOVA TI PLESNEVA SA ZHAKHOV AV
Citation
Vb. Matyushichev et al., EXOGENOUS GANGLIOSIDES MODIFY BIOCHEMICAL-CHANGES ASSOCIATED WITH THEDEVELOPMENT OF FETAL CHICKEN NERVOUS-TISSUE IN CULTURE, Biochemistry, 59(10), 1994, pp. 1103-1107
Citations number
19
Categorie Soggetti
Biology
Journal title
Biochemistry → ACNP
ISSN journal
00062979
Volume
59
Issue
10
Year of publication
1994
Pages
1103 - 1107
Database
ISI
SICI code
0006-2979(1994)59:10<1103:EGMBAW>2.0.ZU;2-T
Abstract
Effects of exogenous ganglioside G(M1) (1 mu M) from bovine brain on m orphology and biochemical characteristics (creatine kinase, acetylchol ine esterase, and adenylate cyclase activity; content of proteins, pho spholipids, and gangliosides) of cells were studied in mixed primary c ultures of fetal chicken brain. Introduction of the ganglioside into t he culture medium accelerated cell growth and differentiation. The con tent of phospho- and glycolipids in such cells was increased. In addit ion, the ganglioside stimulated the activity of several enzymes.