Jv. Byrne et al., ENDOVASCULAR COIL OCCLUSION OF EXPERIMENTAL ANEURYSMS - PARTIAL TREATMENT DOES NOT PREVENT SUBSEQUENT RUPTURE, Neurological research, 16(6), 1994, pp. 425-427
Experimental aneurysms with a high propensity to spontaneous rupture w
ere used to assess the efficacy of endosaccular packing with platinum
coils. Lateral aneurysms, surgically constructed in pigs from vein all
ographs, were untreated or treated by partial or total endovascular pa
cking with coils. All untreated aneurysms (4/4) ruptured and most (3/4
) partially treated aneurysms also ruptured. None of 6 aneurysms in wh
ich the lumen was occluded by 90% or more ruptured or demonstrated reg
rowth on subsequent angiography. Partial treatment was therefore not e
ffective in preventing delayed haemorrhage. These findings suggest tha
t subtotal endovascular treatment may not be protective alter aneurysm
al subarachnoid haemorrhage.