De. Grum et al., PEROXISOMAL BETA-OXIDATION OF FATTY-ACIDS IN BOVINE AND RAT-LIVER, Comparative biochemistry and physiology. B. Comparative biochemistry, 109(2-3), 1994, pp. 281-292
Hepatic peroxisomal beta-oxidation rates were compared in liver homoge
nates from cows and rats during different nutritional and physiologica
l states. Peroxisomal oxidation in liver homogenates from cows represe
nted 50% and 77% of the total capacity for the initial cycle of beta-o
xidation of palmitate and octanoate, respectively, hut only 26% and 65
% for rats. Lactation or food deprivation did not alter rates of hepat
ic peroxisomal beta-oxidation of palmitate or octanoate in cows. Fasti
ng and clofibrate treatment increased rates of total and peroxisomal b
eta-oxidation of palmitate and octanoate in rat liver.