CHARACTERIZATION OF FIBRINOGEN-BINDING PROPERTIES OF ACTINOMYCES-PYOGENES

Authors
LAMMLER C DING H
Citation
C. Lammler et H. Ding, CHARACTERIZATION OF FIBRINOGEN-BINDING PROPERTIES OF ACTINOMYCES-PYOGENES, Journal of veterinary medicine. Series B, 41(9), 1994, pp. 588-596
Citations number
33
Categorie Soggetti
Veterinary Sciences
Journal title
Journal of veterinary medicine. Series B → ACNP
ISSN journal
09311793
Volume
41
Issue
9
Year of publication
1994
Pages
588 - 596
Database
ISI
SICI code
0931-1793(1994)41:9<588:COFPOA>2.0.ZU;2-Q
Abstract
This study was designed to further characterize the fibrinogen-binding properties of Actinomyces pyogenes. The fibrinogen-binding capacities of a selected A. pyogenes culture could be significantly enhanced by heat pretreatment (60 degrees C, 1 h) of the bacteria. The fibrinogen- binding site seemed to be a protein which was specific for fibrinogen. In phagocytosis studies, binding of fibrinogen to A. pyogenes signifi cantly increased the phagocytic capacity of bovine polymorphonuclear l eucocytes.