ENANTIOMERIC DIFFERENTIATION OF A WIDE-RANGE OF PHARMACOLOGICALLY ACTIVE SUBSTANCES BY CYCLODEXTRIN-MODIFIED MICELLAR ELECTROKINETIC CAPILLARY CHROMATOGRAPHY USING A BILE-SALT

Authors
AUMATELL A WELLS RJ
Citation
A. Aumatell et Rj. Wells, ENANTIOMERIC DIFFERENTIATION OF A WIDE-RANGE OF PHARMACOLOGICALLY ACTIVE SUBSTANCES BY CYCLODEXTRIN-MODIFIED MICELLAR ELECTROKINETIC CAPILLARY CHROMATOGRAPHY USING A BILE-SALT, Journal of chromatography, 688(1-2), 1994, pp. 329-337
Citations number
29
Categorie Soggetti
Chemistry Analytical
Journal title
Journal of chromatography → ACNP
Volume
688
Issue
1-2
Year of publication
1994
Pages
329 - 337
Database
ISI
SICI code
Abstract
This paper shows the versatility of modified charged and non-charged b eta-cyclodextrins in micellar systems for optically resolving beta-ago nists, beta-antagonists, phenylethylamines stimulants and diclofensine an antidepressant. A total of 22 compounds were optically resolved us ing hydroxypropyl-beta-cyclodextrin with sodium taurodeoxycholate and sodium sulfobutyl ether-beta-cyclodextrin with sodium dodecyl sulfate.