SYNTHETIC APPLICATIONS OF ARENETRICARBONYLCHROMIUM(0) COMPLEXES - THESYNTHESIS OF POLYFUNCTIONALISED THIOPHENES

Authors
LOFT MS MOWLEM TJ WIDDOWSON DA
Citation
Ms. Loft et al., SYNTHETIC APPLICATIONS OF ARENETRICARBONYLCHROMIUM(0) COMPLEXES - THESYNTHESIS OF POLYFUNCTIONALISED THIOPHENES, Journal of the Chemical Society. Perkin transactions. I, (2), 1995, pp. 97-104
Citations number
40
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Journal of the Chemical Society. Perkin transactions. I → ACNP
ISSN journal
0300922X
Issue
2
Year of publication
1995
Pages
97 - 104
Database
ISI
SICI code
0300-922X(1995):2<97:SAOAC->2.0.ZU;2-Z
Abstract
Lithiation of thiophenetricarbonylchromium(o) complexes with butyllith ium occurs preferentially at C-2/5 but when these are blocked, 3/4 lit hiation is facile. Combinations of a bulky silyl ((Pr3Si)-Si-i or Bu(t )'Me(2)Si) blocking group at C-2/5 and remote lithiation/electrophilic quench of C-3/4 followed by desilylation/lithiation/electrophilic que nch allowed the synthesis of 2,3-. 2,3,5- and 2.3,4,5-polysubstituted thiophene complexes and their derived free thiophenes.