The Coulomb blockade in a small superconducting grain connected to two
macroscopic electrodes by tunnel junctions is discussed. The ground s
tate energy of the grain is sensitive to the parity of the number of e
lectrons on it. For an odd number of electrons, this energy is shifted
by the value of the superconducting gap Delta due to the presence of
one unpaired electron. In the case of superconducting leads, the charg
e parity effects give rise to a threshold behavior of the critical Jos
ephson current when Delta is suppressed below the charging energy E(c)
, e.g., by a magnetic field. The critical current can be periodically
modulated by the voltage of a gate electrostatically coupled to the gr
ain. The character of this modulation changes at the threshold: sharp
peaks of the critical current existing at large values of Delta, split
on two components each when the gap is suppressed, because an odd-num
ber state becomes accessible at certain values of the gate voltage. Si
multaneously, the existence of a quasiparticle at the bottom of a cont
inuous energy spectrum allows the low-bias dissipation in the grain at
an odd-number state. We estimate the dissipative current through a su
perconducting double-junction system. We argue that even at Delta > E(
c) the same dissipation mechanism can be activated if a small finite b
ias is applied, because of ''poisoning'' of the grain with an odd elec
tron.