We study charging effects and tunneling in the single electron box. Tu
nneling mixes different charge states and in the nonperturbative regim
e the charge in the island may be strongly screened. When charge state
s are nearly degenerate the screening of the charge is strong even in
the weak tunneling regime. Virtual tunneling processes reduce both the
level splitting Delta and the tunneling strength alpha. The charge on
the island and the decay rates are calculated. In the strong tunnelin
g regime also nondegenerate states are affected by tunneling. Strong-c
oupling scaling renormalizes the effective capacitance, a result which
we confirm by Monte Carlo simulations. The tunneling strength alpha s
cales to smaller values into the regime where the weak-coupling scalin
g applies. We propose a two-stage scaling procedure providing the unif
ied picture for the problem. The scaling analysis is also extended to
superconducting tunnel junctions with finite subgap conductance.