BLOOD-VISCOSITY AUTOREGULATION FACTOR IN CEREBROVASCULAR ACCIDENTS AND HIGH-RISK CASES - A NEW APPROACH

Autoregulation is an active adaptive reaction by virtue of which cereb ral blood flow remains constant despite variations in perfusion pressu re. There exist an inverse relationship between cerebral blood flow an d the viscosity of blood, The concept of autoregulatory mechanism for blood viscosity was suggested in the recent past. This autoregulatory mechanism which suffer a loss in ischemic stroke cases is quantitative ly presented in the present investigation in terms of power law coeffi cients namely, n and k, through an empirical relation. Further it is s hown that the blood viscosity autoregulation factor (A) in the follow- up stroke cases having no risk factor except age, is restored by seven th day to the range shown for age matched healthy controls. The quanti fication of already existing concept of blood viscosity autoregulation especially with reference to follow-up stroke cases may help the clin icians understand the relationship between the severity of disease and the extent of alteration in the resistance to the flow of blood. This method of analysis may reveal the action of drugs destroying or resto ring the autoregulation in different diseases.