OVARIAN STIMULATION WITH A PROTOCOL USING A LOW-DOSE OF GNRH AGONIST IN PATIENTS WITH ELEVATED BASAL FSH

Citation
F. Olivennes et al., OVARIAN STIMULATION WITH A PROTOCOL USING A LOW-DOSE OF GNRH AGONIST IN PATIENTS WITH ELEVATED BASAL FSH, Contraception fertilite sexualite, 24(12), 1996, pp. 912-916
Citations number
20
Categorie Soggetti
Obsetric & Gynecology
ISSN journal
11651083
Volume
24
Issue
12
Year of publication
1996
Pages
912 - 916
Database
ISI
SICI code
1165-1083(1996)24:12<912:OSWAPU>2.0.ZU;2-R
Abstract
This study compare the ovarian response of patients with high day 3 FS H (> 6,5 UI/L), treated with two protocols; a protocol with a low dose of GnRH agonist and a so called ''long protocol'' with GnRH agonist i n a depot formula. The ovarian response with the agonist low dose was better with less ampules (37, 1 vs 46,6) and a shorter duration of sti mulation (10,5 vs 12,4 days). The number of mature oocyte was higher ( 5,9 vs 4,5) as well as the number of good quality embryo (3,2 versus 2 ,3). The E2 levels on day 8 was also higher (1 065 vs 460 pg/ml). The cancellation rate was lower (14 % vs 26 %). The use of the low dose pr otocol gave a better ovarian response for patients with high day 3 FSH , Large randomized studies are needed to confirm these data.