STEREOCONTROLLED ROUTES TO DERIVATIVES OF CARBONYL-2-AMINO-4-ARYL-5-CYANO-6-PHENYL-4H-PYRANS

Authors
MARTIN N MARTINEZGRAU A SEOANE C MARCO JL
Citation
N. Martin et al., STEREOCONTROLLED ROUTES TO DERIVATIVES OF CARBONYL-2-AMINO-4-ARYL-5-CYANO-6-PHENYL-4H-PYRANS, Tetrahedron : asymmetry, 6(1), 1995, pp. 255-262
Citations number
18
Categorie Soggetti
Chemistry Inorganic & Nuclear","Chemistry Inorganic & Nuclear","Chemistry Physical
Journal title
Tetrahedron : asymmetry → ACNP
ISSN journal
09574166
Volume
6
Issue
1
Year of publication
1995
Pages
255 - 262
Database
ISI
SICI code
0957-4166(1995)6:1<255:SRTDOC>2.0.ZU;2-S
Abstract
The asymmetric Michael addition of cyanoacetates 2b-e and benzoylaceto nitrile 6 to alpha-benzoylcinnamonitrile 3 and alpha-cyanocinnamates 7 b-e, respectively, has been studied. The resulting carbonyl-2-amino-4- aryl-5-cyano-6-phenyl-4H-pyrans 4b-e have been obtained in moderate di astereomeric excess and good chemical yield.