ON THE NATURE OF MUTATIONS IN MOLECULAR EVOLUTION

Authors
Citation
Ma. Soto et J. Toha, ON THE NATURE OF MUTATIONS IN MOLECULAR EVOLUTION, Origins of life and evolution of the biosphere, 25(1-3), 1995, pp. 271-275
Citations number
6
Categorie Soggetti
Biology
ISSN journal
01696149
Volume
25
Issue
1-3
Year of publication
1995
Pages
271 - 275
Database
ISI
SICI code
0169-6149(1995)25:1-3<271:OTNOMI>2.0.ZU;2-Q
Abstract
In this work it is proposed that in evolution amino acid substitutions implying strong physico chemical and structural differences are more relevant and more frequent than substitutions between similar amino ac ids. This analysis is made over a group of protein families representi ng about 10 000 substitutions and as examples the evolutionary trees o f fibrinopeptides A and calcitonins were constructed and compared.