INSIGHTS INTO THE ROLE OF THE HYDROGEN-BOND AND HYDROPHOBIC EFFECT ONRECOGNITION IN MOLECULARLY IMPRINTED POLYMER SYNTHETIC PEPTIDE RECEPTOR MIMICS

Peptide antibody combining site mimics prepared by the molecular impri nting of N-Ac-L-Phe-L-Trp-OMe were used as highly efficient ''tailor-m ade'' chiral stationary phases and for the study of non-ionic non-cova lent interaction-based recognition. The effect of water on recognition and the role of the hydrogen bonding and the hydrophobic effect on li gand selectivity are discussed.