Presently available bipolar pacemakers connected to bipolar leads allo
w the programming of polarity to either bipolar or unipolar configurat
ion. The bipolar configuration improves sensing because of its lack of
oversensing. In respect to the pacing impulse, it may be beneficial t
o program the bipolar to unipolar configuration, because the unipolar
pacing configuration seems to lead to lower pacing thresholds. The aim
of the study was to investigate the effects of the two configurations
on pacing and sensing in 11 patients with a new ventricular steroid-e
luting lead (Encor Dec 033-301, Telectronics Inc.) connected to the sa
me types of VVI(R) pacemakers. Follow-up was 12 months after implantat
ion. Pacing was assessed by pulse duration thresholds at 0.8-, 1.6-, a
nd 2.5-V pulse amplitude and by pacing impedance. Parameters for sensi
ng included sensing thresholds; R wave amplitudes, and amplitude of in
trinsic deflection. Pulse duration thresholds were similar for the two
configurations. At implantation, pacing impedance was significantly h
igher with bipolar (672 +/- 60 Omega) than with unipolar pacing config
uration (626 +/- 82 Omega, P < 0.005). The difference lasted until 1 m
onth after implantation (bipolar: 670 +/- 49 SZ; unipolar: 630 53 Omeg
a, P < 0.01). No significant differences were detected after 3 (bipola
r: 683 +/- 63 Omega; unipolar: 662 +/- 70 Omega) and 12 months (bipola
r: 658 +/- 64 Omega; unipolar: 660 +/- 63 Omega) between the 2 configu
rations. Although intrinsic deflections of ventricular electrograms we
re different, mean R wave amplitudes were similar in unipolar and bipo
lar configuration. Pacing and sensing characteristics of unipolar and
bipolar configuration were similar for the studied bipolar pacing lead
. Pacing impedance was initially higher for bipolar than for unipolar
configuration and equilibrated within 3 months after implantation.