NMR ANALYSIS OF THE ADDITION OF NH, OH AN D P-V-H FUNCTIONAL MOLECULES TO DIETHYL ETHENYLIDENE-BISPHOSPHONATE SYNTHESIS OF FUNCTIONALIZED GEM-BISPHOSPHONATES
T. Bailly et R. Burgada, NMR ANALYSIS OF THE ADDITION OF NH, OH AN D P-V-H FUNCTIONAL MOLECULES TO DIETHYL ETHENYLIDENE-BISPHOSPHONATE SYNTHESIS OF FUNCTIONALIZED GEM-BISPHOSPHONATES, Phosphorus, sulfur and silicon and the related elements, 86(1-4), 1994, pp. 217-228
Tetraethyl ethenylidene bis phosphonate can undergo facile Michael typ
e addition reaction with amines, alcohols, water, aminoacid and spirop
hosphoranes bearing a P-H bond. The stability of these compounds was i
nvestigated and the reversibility of the reaction was demonstrated in
the case of methylamine.