A SEQUENTIAL APPROACH TO TESTING WITH THE RODENT BONE-MARROW MICRONUCLEUS ASSAY - OBVIATION OF THE NEED FOR STATISTICAL-ANALYSES OF DATA

Authors
ASHBY J TINWELL H
Citation
J. Ashby et H. Tinwell, A SEQUENTIAL APPROACH TO TESTING WITH THE RODENT BONE-MARROW MICRONUCLEUS ASSAY - OBVIATION OF THE NEED FOR STATISTICAL-ANALYSES OF DATA, Mutation research, 327(1-2), 1995, pp. 49-55
Citations number
15
Categorie Soggetti
Genetics & Heredity",Biology,"Biothechnology & Applied Migrobiology
Journal title
Mutation research → ACNP
ISSN journal
00275107
Volume
327
Issue
1-2
Year of publication
1995
Pages
49 - 55
Database
ISI
SICI code
0027-5107(1995)327:1-2<49:ASATTW>2.0.ZU;2-U
Abstract
The 'sequential' protocol we use for the conduct of mouse bone marrow micronucleus assays is described. The most important criterion for act ivity in the assay is the reproducibility of any induced effects. The frequencies of micronucleated polychromatic erythrocytes among 239 mal e CBA control mice are displayed and discussed. Our decision to avoid statistical analysis when assessing mouse bone marrow micronucleus dat a is explained.